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Mitoxantrone induces apoptosis in osteosarcoma cells through regulation of the Akt/FOXO3 pathway

The outcome of chemotherapy for osteosarcoma have improved during the past decade and more patients have access to combination chemotherapy, but there has been no significant clinical progress in the patient survival rate. Recently, forkhead-box O3 (FOXO3) was identified as a pivotal transcription f...

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Detalles Bibliográficos
Publicado en:Oncol Lett
Autores principales: Park, See-Hyoung, Lee, Jongsung, Kang, Mi-Ae, Jang, Kyu Yun, Kim, Jung Ryul
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004704/
https://ncbi.nlm.nih.gov/pubmed/29928344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8547
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