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Metformin coordinates osteoblast/osteoclast differentiation associated with ischemic osteonecrosis
In this study, we aimed to identify a candidate drug that can activate endogenous Angiopoietin 1 (Ang1) expression via drug repositioning as a pharmacological treatment for avascular osteonecrosis. After incubation with 821 drugs from the Food and Drug Administration (FDA)-approved drug library, Ang...
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| Publié dans: | Aging (Albany NY) |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138543/ https://ncbi.nlm.nih.gov/pubmed/32045366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102796 |
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