MicroRNA-410-3p attenuates gemcitabine resistance in pancreatic ductal adenocarcinoma by inhibiting HMGB1-mediated autophagy

Gemcitabine-based chemotherapy is the most common treatment option for pancreatic ductal adenocarcinoma (PDAC). However, it offers little therapeutic value in many cases due to the rapid development of chemoresistance. MicroRNAs (miRNAs) have been found to play pivotal roles in the chemotherapeutic...

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Pubblicato in:Oncotarget
Autori principali: Xiong, Junjie, Wang, Dan, Wei, Ailin, Ke, Nengwen, Wang, Yichao, Tang, Jie, He, Sirong, Hu, Weiming, Liu, Xubao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746084/
https://ncbi.nlm.nih.gov/pubmed/29296182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22494
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