MicroRNA-410-3p attenuates gemcitabine resistance in pancreatic ductal adenocarcinoma by inhibiting HMGB1-mediated autophagy

Gemcitabine-based chemotherapy is the most common treatment option for pancreatic ductal adenocarcinoma (PDAC). However, it offers little therapeutic value in many cases due to the rapid development of chemoresistance. MicroRNAs (miRNAs) have been found to play pivotal roles in the chemotherapeutic...

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Publicat a:Oncotarget
Autors principals: Xiong, Junjie, Wang, Dan, Wei, Ailin, Ke, Nengwen, Wang, Yichao, Tang, Jie, He, Sirong, Hu, Weiming, Liu, Xubao
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746084/
https://ncbi.nlm.nih.gov/pubmed/29296182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22494
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