The Potent Oncogene NPM-ALK Mediates Malignant Transformation of Normal Human CD4(+) T Lymphocytes

With this study we have demonstrated that in vitro transduction of normal human CD4(+) T lymphocytes with NPM-ALK results in their malignant transformation. The transformed cells become immortalized and display morphology and immunophenotype characteristic of patient-derived anaplastic large-cell ly...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Am J Pathol
Hoofdauteurs: Zhang, Qian, Wei, Fang, Wang, Hong Yi, Liu, Xiaobin, Roy, Darshan, Xiong, Qun-Bin, Jiang, Shuguang, Medvec, Andrew, Danet-Desnoyers, Gwenn, Watt, Christopher, Tomczak, Ewa, Kalos, Michael, Riley, James L., Wasik, Mariusz A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2013
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745542/
https://ncbi.nlm.nih.gov/pubmed/24404580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.08.030
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items