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Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B(12)–Deprivation Optic Neuropathy

Chronic deficiency of vitamin B(12) is the only nutritional deficiency definitively proved to cause optic neuropathy and loss of vision. The mechanism by which this occurs is unknown. Optic neuropathies are associated with death of retinal ganglion cells (RGCs), neurons that project their axons alon...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Pathol
Hauptverfasser: Chan, Wesley, Almasieh, Mohammadali, Catrinescu, Maria-Magdalena, Levin, Leonard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745528/
https://ncbi.nlm.nih.gov/pubmed/29037851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.032
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