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Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B(12)–Deprivation Optic Neuropathy

Chronic deficiency of vitamin B(12) is the only nutritional deficiency definitively proved to cause optic neuropathy and loss of vision. The mechanism by which this occurs is unknown. Optic neuropathies are associated with death of retinal ganglion cells (RGCs), neurons that project their axons alon...

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Detalles Bibliográficos
Publicado en:Am J Pathol
Main Authors: Chan, Wesley, Almasieh, Mohammadali, Catrinescu, Maria-Magdalena, Levin, Leonard A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745528/
https://ncbi.nlm.nih.gov/pubmed/29037851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.032
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