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Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B(12)–Deprivation Optic Neuropathy

Chronic deficiency of vitamin B(12) is the only nutritional deficiency definitively proved to cause optic neuropathy and loss of vision. The mechanism by which this occurs is unknown. Optic neuropathies are associated with death of retinal ganglion cells (RGCs), neurons that project their axons alon...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Chan, Wesley, Almasieh, Mohammadali, Catrinescu, Maria-Magdalena, Levin, Leonard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745528/
https://ncbi.nlm.nih.gov/pubmed/29037851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.032
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