Inhibiting the Ca(2+) Influx Induced by Human CSF

One potential therapeutic strategy for Alzheimer’s disease (AD) is to use antibodies that bind to small soluble protein aggregates to reduce their toxic effects. However, these therapies are rarely tested in human CSF before clinical trials because of the lack of sensitive methods that enable the me...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Drews, Anna, De, Suman, Flagmeier, Patrick, Wirthensohn, David C., Chen, Wei-Hsin, Whiten, Daniel R., Rodrigues, Margarida, Vincke, Cécile, Muyldermans, Serge, Paterson, Ross W., Slattery, Catherine F., Fox, Nick C., Schott, Jonathan M., Zetterberg, Henrik, Dobson, Christopher M., Gandhi, Sonia, Klenerman, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745229/
https://ncbi.nlm.nih.gov/pubmed/29241555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.057
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