Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss

Multiple myeloma (MM) is a hematologic cancer characterized by expansion of malignant plasma cells in the bone marrow. Most patients develop an osteolytic bone disease, largely caused by increased osteoclastogenesis. The myeloma bone marrow is hypoxic, and hypoxia may contribute to MM disease progre...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Blood Adv
Huvudupphovsmän: Zahoor, Muhammad, Westhrin, Marita, Aass, Kristin Roseth, Moen, Siv Helen, Misund, Kristine, Psonka-Antonczyk, Katarzyna Maria, Giliberto, Mariaserena, Buene, Glenn, Sundan, Anders, Waage, Anders, Sponaas, Anne-Marit, Standal, Therese
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2017
Ämnen:
Lymphoid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745138/
https://ncbi.nlm.nih.gov/pubmed/29296919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017010801
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk