Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the [Formula: see text] Mouse Model and the Role of As3mt-Mediated Methylation

BACKGROUND: Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains und...

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Bibliografski detalji
Izdano u:Environ Health Perspect
Glavni autori: Negro Silva, Luis Fernando, Lemaire, Maryse, Lemarié, Catherine A., Plourde, Dany, Bolt, Alicia M., Chiavatti, Christopher, Bohle, D. Scott, Slavkovich, Vesna, Graziano, Joseph H., Lehoux, Stéphanie, Mann, Koren K.
Format: Artigo
Jezik:Inglês
Izdano: Environmental Health Perspectives 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744679/
https://ncbi.nlm.nih.gov/pubmed/28728140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP806
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