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Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the [Formula: see text] Mouse Model and the Role of As3mt-Mediated Methylation

BACKGROUND: Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains und...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Environ Health Perspect
Κύριοι συγγραφείς: Negro Silva, Luis Fernando, Lemaire, Maryse, Lemarié, Catherine A., Plourde, Dany, Bolt, Alicia M., Chiavatti, Christopher, Bohle, D. Scott, Slavkovich, Vesna, Graziano, Joseph H., Lehoux, Stéphanie, Mann, Koren K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Environmental Health Perspectives 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744679/
https://ncbi.nlm.nih.gov/pubmed/28728140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP806
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