Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the [Formula: see text] Mouse Model and the Role of As3mt-Mediated Methylation

BACKGROUND: Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains und...

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Bibliographic Details
Published in:Environ Health Perspect
Main Authors: Negro Silva, Luis Fernando, Lemaire, Maryse, Lemarié, Catherine A., Plourde, Dany, Bolt, Alicia M., Chiavatti, Christopher, Bohle, D. Scott, Slavkovich, Vesna, Graziano, Joseph H., Lehoux, Stéphanie, Mann, Koren K.
Format: Artigo
Language:Inglês
Published: Environmental Health Perspectives 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744679/
https://ncbi.nlm.nih.gov/pubmed/28728140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP806
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