Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the [Formula: see text] Mouse Model and the Role of As3mt-Mediated Methylation

BACKGROUND: Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains und...

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Publicado en:Environ Health Perspect
Autores principales: Negro Silva, Luis Fernando, Lemaire, Maryse, Lemarié, Catherine A., Plourde, Dany, Bolt, Alicia M., Chiavatti, Christopher, Bohle, D. Scott, Slavkovich, Vesna, Graziano, Joseph H., Lehoux, Stéphanie, Mann, Koren K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Environmental Health Perspectives 2017
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744679/
https://ncbi.nlm.nih.gov/pubmed/28728140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP806
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