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Genetic Deletion of LXRα Prevents Arsenic-Enhanced Atherosclerosis, But Not Arsenic-Altered Plaque Composition
Arsenic exposure has been linked to an increased incidence of atherosclerosis. Previously, we have shown in vitro and in vivo that arsenic inhibits transcriptional activation of the liver X receptors (LXRs), key regulators of lipid homeostasis. Therefore, we evaluated the role of LXRα in arsenic-ind...
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| Publicado no: | Toxicol Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250850/ https://ncbi.nlm.nih.gov/pubmed/25273567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu197 |
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