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Genetic Deletion of LXRα Prevents Arsenic-Enhanced Atherosclerosis, But Not Arsenic-Altered Plaque Composition
Arsenic exposure has been linked to an increased incidence of atherosclerosis. Previously, we have shown in vitro and in vivo that arsenic inhibits transcriptional activation of the liver X receptors (LXRs), key regulators of lipid homeostasis. Therefore, we evaluated the role of LXRα in arsenic-ind...
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| Udgivet i: | Toxicol Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250850/ https://ncbi.nlm.nih.gov/pubmed/25273567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu197 |
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