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Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors
Boronic acid transition state inhibitors (BATSIs) represent one of the most promising class of β-lactamase inhibitors. Here we describe a new class of BATSIs, namely 1-amido-2-triazolylethaneboronic acids, which were synthesized combining the asymmetric homologation of boronates with Copper-Catalyze...
Sparad:
| I publikationen: | J Med Chem |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5744665/ https://ncbi.nlm.nih.gov/pubmed/26102369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00341 |
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