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Synthesis of 1,2,3-triazol-1-yl-methaneboronic acids via click chemistry: an easy access to a new potential scaffold for protease inhibitors

Stereoselective synthesis of previously unreported 1,2,3-triazol-1-yl-methaneboronic acids has been achieved from azidomethaneboronates by Copper-catalyzed Azide-Alkyne Cycloaddition (CuAAC). The proximity of the cycloaddition reaction center to the boronic group is not detrimental for the stability...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: Romagnoli, Chiara, Caselli, Emilia, Prati, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527660/
https://ncbi.nlm.nih.gov/pubmed/26257579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201403408
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