Brucein D, a Naturally Occurring Tetracyclic Triterpene Quassinoid, Induces Apoptosis in Pancreatic Cancer through ROS-Associated PI3K/Akt Signaling Pathway

Brucein D (BD), a major active quassinoid in Brucea javanica, has exhibited pronounced anticancer activities. However, the biologic mechanisms have not been fully explored. In this study, BD exhibited more potent cytotoxic effect on pancreatic cancer (PanCa) cell lines, while exerted weaker cytotoxi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Lai, Zheng-Quan, Ip, Siu-Po, Liao, Hui-Jun, Lu, Zheng, Xie, Jian-Hui, Su, Zi-Ren, Chen, Yun-Long, Xian, Yan-Fang, Leung, Po-Sing, Lin, Zhi-Xiu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744014/
https://ncbi.nlm.nih.gov/pubmed/29311937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00936
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker