Nivolumab Enhances In Vitro Effector Functions of PD-1(+) T-Lymphocytes and Leishmania-Infected Human Myeloid Cells in a Host Cell-Dependent Manner

Functional impairment of T-cells and a concomitant augmented expression of programmed death-1 (PD-1) have been observed in visceral leishmaniasis patients, as well as in experimental models for visceral and cutaneous leishmaniasis. The PD-1/PD-1-ligand (PD-1/PD-L) interaction negatively regulates T-...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Filippis, Christodoulos, Arens, Katharina, Noubissi Nzeteu, Gaetan Aime, Reichmann, Gabriele, Waibler, Zoe, Crauwels, Peter, van Zandbergen, Ger
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743744/
https://ncbi.nlm.nih.gov/pubmed/29312350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01880
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