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Nivolumab Enhances In Vitro Effector Functions of PD-1(+) T-Lymphocytes and Leishmania-Infected Human Myeloid Cells in a Host Cell-Dependent Manner
Functional impairment of T-cells and a concomitant augmented expression of programmed death-1 (PD-1) have been observed in visceral leishmaniasis patients, as well as in experimental models for visceral and cutaneous leishmaniasis. The PD-1/PD-1-ligand (PD-1/PD-L) interaction negatively regulates T-...
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| Pubblicato in: | Front Immunol |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5743744/ https://ncbi.nlm.nih.gov/pubmed/29312350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01880 |
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