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DnaC, the indispensable companion of DnaB helicase, controls the accessibility of DnaB helicase by primase

Former studies relying on hydrogen/deuterium exchange analysis suggest that DnaC bound to DnaB alters the conformation of the N-terminal domain (NTD) of DnaB to impair the ability of this DNA helicase to interact with primase. Supporting this idea, the work described herein based on biosensor experi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Felczak, Magdalena M., Chodavarapu, Sundari, Kaguni, Jon M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743064/
https://ncbi.nlm.nih.gov/pubmed/29070678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807644
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