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The bacterial DnaC helicase loader is a DnaB ring breaker

Dedicated AAA+ ATPases help deposit hexameric ring-shaped helicases onto DNA to promote replication in cellular organisms. To understand how loading occurs, we used negative-stain electron microscopy and small-angle X-ray scattering to determine the ATP-bound structure of the intact E. coli DnaB•Dna...

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Bibliografske podrobnosti
Main Authors: Arias-Palomo, Ernesto, O’Shea, Valerie L., Hood, Iris V., Berger, James M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670212/
https://ncbi.nlm.nih.gov/pubmed/23562643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.006
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