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Primase Directs the Release of DnaC from DnaB

An AAA+ ATPase, DnaC delivers DnaB helicase at the E. coli chromosomal origin by a poorly understood process. This report shows that mutant proteins bearing alanine substitutions for two conserved arginines in a motif named box VII are defective in DNA replication, but this deficiency does not arise...

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Bibliographic Details
Main Authors: Makowska-Grzyska, Magdalena, Kaguni, Jon M.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819048/
https://ncbi.nlm.nih.gov/pubmed/20129058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.031
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