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Accomplices of the Hypoxic Tumor Microenvironment Compromising Antitumor Immunity: Adenosine, Lactate, Acidosis, Vascular Endothelial Growth Factor, Potassium Ions, and Phosphatidylserine

In this minireview, we aim to highlight key factors of the tumor microenvironment, including adenosine, lactate, acidosis, vascular endothelial growth factor, phosphatidylserine, high extracellular K(+) levels, and tumor hypoxia with respect to antitumor immune functions. Most solid tumors have an i...

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書誌詳細
出版年:Front Immunol
主要な著者: Vaupel, Peter, Multhoff, Gabriele
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742577/
https://ncbi.nlm.nih.gov/pubmed/29312351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01887
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