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Accomplices of the Hypoxic Tumor Microenvironment Compromising Antitumor Immunity: Adenosine, Lactate, Acidosis, Vascular Endothelial Growth Factor, Potassium Ions, and Phosphatidylserine

In this minireview, we aim to highlight key factors of the tumor microenvironment, including adenosine, lactate, acidosis, vascular endothelial growth factor, phosphatidylserine, high extracellular K(+) levels, and tumor hypoxia with respect to antitumor immune functions. Most solid tumors have an i...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Vaupel, Peter, Multhoff, Gabriele
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742577/
https://ncbi.nlm.nih.gov/pubmed/29312351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01887
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