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Blunting of estrogen modulation of cardiac cellular chymase/RAS activity and function in SHR

The relatively low efficacy of ACE-inhibitors in the treatment of heart failure in women after estrogen loss may be due to their inability to reach the intracellular sites at which angiotensin (Ang) II is generated and/or the existence of cell-specific mechanisms in which ACE is not the essential pr...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Ahmad, Sarfaraz, Sun, Xuming, Lin, Marina, Varagic, Jasmina, Zapata-Sudo, Gisele, Ferrario, Carlos M., Groban, Leanne, Wang, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741475/
https://ncbi.nlm.nih.gov/pubmed/28888034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26179
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