Homeostatic control of Hpo/MST kinase activity through autophosphorylation-dependent recruitment of the STRIPAK PP2A phosphatase complex

The Hippo pathway controls organ size and tissue homeostasis through a kinase cascade leading from the Ste20-like kinase Hpo (MST1/2 in mammals) to the transcriptional coactivator Yki (YAP/TAZ in mammals). While previous studies have uncovered positive and negative regulators of Hpo/MST, how they ar...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Zheng, Yonggang, Liu, Bo, Wang, Li, Lei, Huiyan, Prieto, Katiuska Daniela Pulgar, Pan, Duojia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741103/
https://ncbi.nlm.nih.gov/pubmed/29262338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.076
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky