Protective effects of agonists of growth hormone-releasing hormone (GHRH) in early experimental diabetic retinopathy

The potential therapeutic effects of agonistic analogs of growth hormone-releasing hormone (GHRH) and their mechanism of action were investigated in diabetic retinopathy (DR). Streptozotocin-induced diabetic rats (STZ-rats) were treated with 15 μg/kg GHRH agonist, MR-409, or GHRH antagonist, MIA-602...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Thounaojam, Menaka C., Powell, Folami L., Patel, Sagar, Gutsaeva, Diana R., Tawfik, Amany, Smith, Sylvia B., Nussbaum, Julian, Block, Norman L., Martin, Pamela M., Schally, Andrew V., Bartoli, Manuela
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740669/
https://ncbi.nlm.nih.gov/pubmed/29180438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718592114
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