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Role of Endothelial ADAM17 in Early Vascular Changes Associated with Diabetic Retinopathy

ADAM17, a disintegrin and metalloproteinase 17, is a transmembrane metalloproteinase that regulates bioavailability of multiple membrane-bound proteins via ectodomain shedding. ADAM17 activity was shown to contribute to a number of vascular pathologies, but its role in the context of diabetic retino...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Shalaby, Lamiaa, Thounaojam, Menaka, Tawfik, Amany, Li, Junnan, Hussein, Khaled, Jahng, Wan Jin, Al-Shabrawey, Mohamed, Kwok, Hang Fai, Bartoli, Manuela, Gutsaeva, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073770/
https://ncbi.nlm.nih.gov/pubmed/32024241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9020400
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