In Vivo Bioluminescent Monitoring of Therapeutic Efficacy and Pharmacodynamic Target Assessment of Antofloxacin against Escherichia coli in a Neutropenic Murine Thigh Infection Model

Antimicrobial resistance among uropathogens has increased the rates of infection-related morbidity and mortality. Antofloxacin is a novel fluoroquinolone with broad-spectrum antibacterial activity against urinary Gram-negative bacilli, such as Escherichia coli. This study monitored the in vivo effic...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Zhou, Yu-Feng, Tao, Meng-Ting, He, Yu-Zhang, Sun, Jian, Liu, Ya-Hong, Liao, Xiao-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740385/
https://ncbi.nlm.nih.gov/pubmed/29038275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01281-17
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