Pharmacodynamic Profile of Ertapenem against Klebsiella pneumoniae and Escherichia coli in a Murine Thigh Model

The pharmacodynamic profile of ertapenem was evaluated in a neutropenic mouse thigh infection model. Extended-spectrum beta-lactamase (ESBL)-positive and ESBL-negative clinical strains of Escherichia coli and Klebsiella pneumoniae were studied. MICs ranged from 0.0078 to 0.06 μg/ml with standard ino...

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Detalhes bibliográficos
Main Authors: Maglio, Dana, Banevicius, Mary Anne, Sutherland, Christina, Babalola, Chinedum, Nightingale, Charles H., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538873/
https://ncbi.nlm.nih.gov/pubmed/15616306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.276-280.2005
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