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Pharmacodynamic Assessment of Ertapenem (MK-0826) against Streptococcus pneumoniae in a Murine Neutropenic Thigh Infection Model

The objective of this study was to determine the susceptibility breakpoint of a new carbapenem, ertapenem (MK-0826), against Streptococcus pneumoniae strains based on bacterial density and survival studies in a murine thigh infection model. Sixteen S. pneumoniae isolates for which MICs ranged from 0...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Xuan, Dawei, Banevicius, Maryanne, Capitano, Blair, Kim, Myo-Kyoung, Nightingale, Charles, Nicolau, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127426/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.9.2990-2995.2002
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