Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5‐HT(1A) receptor‐mediated suppression of nausea and anxiety in rats

BACKGROUND AND PURPOSE: The aim of this study was to compare the abilities of cannabidiolic acid methyl ester (HU‐580) and cannabidiolic acid (CBDA) to enhance 5‐HT(1A) receptor activation in vitro and produce 5‐HT(1A)‐mediated reductions in nausea and anxiety in vivo. EXPERIMENTAL APPROACH: We inve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Pertwee, Roger G, Rock, Erin M, Guenther, Kelsey, Limebeer, Cheryl L, Stevenson, Lesley A, Haj, Christeene, Smoum, Reem, Parker, Linda A, Mechoulam, Raphael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740240/
https://ncbi.nlm.nih.gov/pubmed/29057454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14073
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