Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway

Doxycycline displays high efficiency for cancer therapy. However, the molecular mechanism is poorly understood. In our previous study, doxycycline was found to suppress tumor progression by directly targeting proteinase-activated receptor 1 (PAR1). In this study, microRNAs were found to be involved...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhong, Weilong, Chen, Shuang, Qin, Yuan, Zhang, Heng, Wang, Hongzhi, Meng, Jing, Huai, Longcong, Zhang, Qiang, Yin, Tingting, Lei, Yueyang, Han, Jingxia, He, Lingfei, Sun, Bo, Liu, Huijuan, Liu, Yanrong, Zhou, Honggang, Sun, Tao, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739605/
https://ncbi.nlm.nih.gov/pubmed/29285218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20418
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