Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway

Doxycycline displays high efficiency for cancer therapy. However, the molecular mechanism is poorly understood. In our previous study, doxycycline was found to suppress tumor progression by directly targeting proteinase-activated receptor 1 (PAR1). In this study, microRNAs were found to be involved...

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Vydáno v:Oncotarget
Hlavní autoři: Zhong, Weilong, Chen, Shuang, Qin, Yuan, Zhang, Heng, Wang, Hongzhi, Meng, Jing, Huai, Longcong, Zhang, Qiang, Yin, Tingting, Lei, Yueyang, Han, Jingxia, He, Lingfei, Sun, Bo, Liu, Huijuan, Liu, Yanrong, Zhou, Honggang, Sun, Tao, Yang, Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739605/
https://ncbi.nlm.nih.gov/pubmed/29285218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20418
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