Polyphyllin I suppresses the formation of vasculogenic mimicry via Twist1/VE-cadherin pathway

Vasculogenic mimicry (VM) is a functional microcirculation pattern formed by aggressive tumor cells and is related to the metastasis and poor prognosis of many cancer types, including hepatocellular carcinoma (HCC). Thus far, no effective drugs have been developed to target VM. In this study, patien...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Xiao, Ting, Zhong, Weilong, Zhao, Jianmin, Qian, Baoxin, Liu, Huijuan, Chen, Shuang, Qiao, Kailiang, Lei, Yueyang, Zong, Shumin, Wang, Hongzhi, Liang, Yuan, Zhang, Heng, Meng, Jing, Zhou, Honggang, Sun, Tao, Liu, Yanrong, Yang, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125388/
https://ncbi.nlm.nih.gov/pubmed/30185783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0902-5
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