6-Gingerol stabilized the p-VEGFR2/VE-cadherin/β-catenin/actin complex promotes microvessel normalization and suppresses tumor progression

BACKGROUND: Anti-angiogenic therapies demonstrate anti-tumor effects by decreasing blood supply to tumors and inhibiting tumor growth. However, anti-angiogenic therapy may leads to changes in tumor microenvironment and increased invasiveness of tumor cells, which in turn promotes distant metastasis...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhong, Weilong, Yang, Wendong, Qin, Yuan, Gu, Wenguang, Xue, Yinyin, Tang, Yuanhao, Xu, Hengwei, Wang, Hongzhi, Zhang, Chao, Wang, Changhua, Sun, Bo, Liu, Yanrong, Liu, Huijuan, Zhou, Honggang, Chen, Shuang, Sun, Tao, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604152/
https://ncbi.nlm.nih.gov/pubmed/31266540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1291-z
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