Computationally-driven identification of antibody epitopes

Understanding where antibodies recognize antigens can help define mechanisms of action and provide insights into progression of immune responses. We investigate the extent to which information about binding specificity implicitly encoded in amino acid sequence can be leveraged to identify antibody e...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Hua, Casey K, Gacerez, Albert T, Sentman, Charles L, Ackerman, Margaret E, Choi, Yoonjoo, Bailey-Kellogg, Chris
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Structural Biology and Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739537/
https://ncbi.nlm.nih.gov/pubmed/29199956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29023
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