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EpiSweep: Computationally-driven Reengineering of Therapeutic Proteins to Reduce immunogenicity while Maintaining Function

Therapeutic proteins are yielding ever more advanced and efficacious new drugs, but the biological origins of these highly effective therapeutics renders them subject to immune surveillance within the patient’s body. When recognized by the immune system as a foreign agent, protein drugs elicit a coo...

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Bibliografski detalji
Izdano u:Methods Mol Biol
Glavni autori: Choi, Yoonjoo, Verma, Deeptak, Griswold, Karl E., Bailey-Kellogg, Chris
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142831/
https://ncbi.nlm.nih.gov/pubmed/27914063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6637-0_20
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