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HIF-1α Deletion in the Endothelium, but Not in the Epithelium, Protects From Radiation-Induced Enteritis

BACKGROUND & AIMS: Radiation therapy in the pelvic area is associated with side effects that impact the quality of life of cancer survivors. Interestingly, the gastrointestinal tract is able to adapt to significant changes in oxygen availability, suggesting that mechanisms related to hypoxia sen...

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Dettagli Bibliografici
Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Toullec, Aurore, Buard, Valérie, Rannou, Emilie, Tarlet, Georges, Guipaud, Olivier, Robine, Sylvie, Iruela-Arispe, M. Luisa, François, Agnès, Milliat, Fabien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738457/
https://ncbi.nlm.nih.gov/pubmed/29276749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.08.001
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