HIF-1α Deletion in the Endothelium, but Not in the Epithelium, Protects From Radiation-Induced Enteritis

BACKGROUND & AIMS: Radiation therapy in the pelvic area is associated with side effects that impact the quality of life of cancer survivors. Interestingly, the gastrointestinal tract is able to adapt to significant changes in oxygen availability, suggesting that mechanisms related to hypoxia sen...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Toullec, Aurore, Buard, Valérie, Rannou, Emilie, Tarlet, Georges, Guipaud, Olivier, Robine, Sylvie, Iruela-Arispe, M. Luisa, François, Agnès, Milliat, Fabien
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738457/
https://ncbi.nlm.nih.gov/pubmed/29276749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.08.001
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