HIF-1α Deletion in the Endothelium, but Not in the Epithelium, Protects From Radiation-Induced Enteritis

BACKGROUND & AIMS: Radiation therapy in the pelvic area is associated with side effects that impact the quality of life of cancer survivors. Interestingly, the gastrointestinal tract is able to adapt to significant changes in oxygen availability, suggesting that mechanisms related to hypoxia sen...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Toullec, Aurore, Buard, Valérie, Rannou, Emilie, Tarlet, Georges, Guipaud, Olivier, Robine, Sylvie, Iruela-Arispe, M. Luisa, François, Agnès, Milliat, Fabien
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738457/
https://ncbi.nlm.nih.gov/pubmed/29276749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.08.001
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