HIF-1α Deletion in the Endothelium, but Not in the Epithelium, Protects From Radiation-Induced Enteritis

BACKGROUND & AIMS: Radiation therapy in the pelvic area is associated with side effects that impact the quality of life of cancer survivors. Interestingly, the gastrointestinal tract is able to adapt to significant changes in oxygen availability, suggesting that mechanisms related to hypoxia sen...

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Bibliographic Details
Published in:Cell Mol Gastroenterol Hepatol
Main Authors: Toullec, Aurore, Buard, Valérie, Rannou, Emilie, Tarlet, Georges, Guipaud, Olivier, Robine, Sylvie, Iruela-Arispe, M. Luisa, François, Agnès, Milliat, Fabien
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738457/
https://ncbi.nlm.nih.gov/pubmed/29276749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.08.001
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