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Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides
Antisense oligonucleotides (ASOs) are versatile tools that can regulate multiple steps of RNA biogenesis in cells and living organisms. Significant improvements in delivery, potency, and stability have been achieved through modifications within the oligonucleotide backbone, sugar and heterocycles. H...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737868/ https://ncbi.nlm.nih.gov/pubmed/28977508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx709 |
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