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Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides

Antisense oligonucleotides (ASOs) are versatile tools that can regulate multiple steps of RNA biogenesis in cells and living organisms. Significant improvements in delivery, potency, and stability have been achieved through modifications within the oligonucleotide backbone, sugar and heterocycles. H...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Bailey, Jeffrey K., Shen, Wen, Liang, Xue-hai, Crooke, Stanley T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737868/
https://ncbi.nlm.nih.gov/pubmed/28977508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx709
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