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Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages
Although the RNase H-dependent mechanism of inhibition of gene expression by chemically modified antisense oligonucleotides (ASOs) has been well characterized, little is known about the interactions between ASOs and intracellular proteins that may alter cellular localization and/or potency of ASOs....
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357732/ https://ncbi.nlm.nih.gov/pubmed/25712094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv143 |
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