Hodgkin Lymphoma: A Complex Metabolic Ecosystem with Glycolytic Reprogramming of the Tumor Microenvironment

BACKGROUND: Twenty percent of patients with classical Hodgkin Lymphoma (cHL) have aggressive disease defined as relapsed or refractory disease to initial therapy. At present we cannot identify these patients pre-treatment. The microenvironment is very important in cHL since non-cancer cells constitu...

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Veröffentlicht in:Semin Oncol
Hauptverfasser: Mikkilineni, Lekha, Whitaker-Menezes, Diana, Domingo-Vidal, Marina, Sprandio, John, Avena, Paola, Cotzia, Paolo, Dulau-Florea, Alina, Gong, Jerald, Uppal, Guldeep, Zhan, Tingting, Leiby, Benjamin, Lin, Zhao, Pro, Barbara, Sotgia, Federica, Lisanti, Michael P., Martinez-Outschoorn, Ubaldo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737784/
https://ncbi.nlm.nih.gov/pubmed/29248133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2017.10.003
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