Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide–MHC Complexes for T-Cell Receptor Immunotherapy

T-cell receptor (TCR) immunotherapy uses T cells engineered with new TCRs to enable detection and killing of cancer cells. Efficacy of TCR immunotherapy depends on targeting antigenic peptides that are efficiently presented by the best-suited major histocompatibility complex (MHC) molecules of cance...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Lorenz, Felix K.M., Ellinger, Christian, Kieback, Elisa, Wilde, Susanne, Lietz, Maria, Schendel, Dolores J., Uckert, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737719/
https://ncbi.nlm.nih.gov/pubmed/28950731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.122
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