N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing

N6-methyladenosine (m(6)A) is the most abundant base modification found in messenger RNAs (mRNAs). The discovery of FTO as the first m(6)A mRNA demethylase established the concept of reversible RNA modification. Here, we present a comprehensive transcriptome-wide analysis of RNA demethylation and un...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Bartosovic, Marek, Molares, Helena Covelo, Gregorova, Pavlina, Hrossova, Dominika, Kudla, Grzegorz, Vanacova, Stepanka
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737695/
https://ncbi.nlm.nih.gov/pubmed/28977517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx778
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items