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N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5

N(6)-Methyladenosine (m6A) is currently one of the most intensively studied post-transcriptional modifications in RNA. Due to its critical role in epigenetics and physiological links to several human diseases, it is also of tremendous biological and medical interest. The m6A mark is dynamically reve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860565/
https://ncbi.nlm.nih.gov/pubmed/27156733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25677
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