RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3′-end extended forms of snRNAs

The Nuclear Exosome Targeting (NEXT) complex is a key cofactor of the mammalian nuclear exosome in the removal of Promoter Upstream Transcripts (PROMPTs) and potentially aberrant forms of other noncoding RNAs, such as snRNAs. NEXT is composed of three subunits SKIV2L2, ZCCHC8 and RBM7. We have recen...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Hrossova, Dominika, Sikorsky, Tomas, Potesil, David, Bartosovic, Marek, Pasulka, Josef, Zdrahal, Zbynek, Stefl, Richard, Vanacova, Stepanka
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417160/
https://ncbi.nlm.nih.gov/pubmed/25852104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv240
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