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RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3′-end extended forms of snRNAs

The Nuclear Exosome Targeting (NEXT) complex is a key cofactor of the mammalian nuclear exosome in the removal of Promoter Upstream Transcripts (PROMPTs) and potentially aberrant forms of other noncoding RNAs, such as snRNAs. NEXT is composed of three subunits SKIV2L2, ZCCHC8 and RBM7. We have recen...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Hrossova, Dominika, Sikorsky, Tomas, Potesil, David, Bartosovic, Marek, Pasulka, Josef, Zdrahal, Zbynek, Stefl, Richard, Vanacova, Stepanka
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417160/
https://ncbi.nlm.nih.gov/pubmed/25852104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv240
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