Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs

The mechanisms of gene expression regulation by miRNAs have been extensively studied. However, the regulation of miRNA function and decay has long remained enigmatic. Only recently, 3′ uridylation via LIN28A-TUT4/7 has been recognized as an essential component controlling the biogenesis of let-7 miR...

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Bibliografiska uppgifter
Huvudupphovsmän: Ustianenko, Dmytro, Hrossova, Dominika, Potesil, David, Chalupnikova, Katerina, Hrazdilova, Kristyna, Pachernik, Jiri, Cetkovska, Katerina, Uldrijan, Stjepan, Zdrahal, Zbynek, Vanacova, Stepanka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2013
Ämnen:
Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884668/
https://ncbi.nlm.nih.gov/pubmed/24141620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.040055.113
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